Toads In the skins of toads there is a substance called "bufotenine", which is a hallucinogen. Procedure for isolating bufotenine from toad skins 1. Collect five to ten toads. Make sure they're toads, as frogs will not work. The best kind are tree toads. 2. Kill them as painlessly as possible, and skin immediately. 3. Allow the skins to dry in a refrigerator for four to five days, or until the skins are brittle. 4. Now crush into a powder and smoke. (Due to its bad taste, it should be mixed with mint or some other fragrant smoking medium.) 5. Enjoy yourself, it's legal, but pray there's not reincarnation.